MUSIC imaging and Noniterative Retrieval of Small Scatterers

Speaker: 

Xudong Chen

Institution: 

National University of Singapore (visiting Stanford)

Time: 

Monday, November 26, 2012 - 4:00pm to 5:00pm

Location: 

RH306

The electromagnetic inverse scattering problem of determining the locations and polarization tensors of a collection of small scatterers is investigated. The locations of scatterers are determined by the multiple signal classification (MUSIC) method and the polarization tensors are retrieved by the two-step least squares method. Multiple scattering effect is taken into account and the inverse scattering problem is nonlinear. However, the proposed method does not involve iterative evaluations of the corresponding forward scattering problem. In addition, the method provides better imaging resolution than the standard MUSIC does, and applies to degenerate scatterers to which the standard MUSIC does not apply. The underlying mathematical principle and physical insight are discussed in detail.

Noise Attenuation during the Development of Spatial Pattern

Speaker: 

Lei Zhang

Institution: 

City University of Hong Kong

Time: 

Monday, November 19, 2012 - 4:00pm to 4:45pm

Host: 

Location: 

RH306

During development and regeneration of a biological system, different types of cells are organized in a precise spatial pattern to achieve different biological functions. To establish a desirable spatial arrangement of various cells, such as stem cells and terminated differentiated cells, the biological host has to utilize many biological processes including diffusible molecules, feedback regulations on cell lineages, and growth. In this talk, we study how interaction among multiple morphogens and their regulations on cell differentiation capability can robustly control stability of regeneration. We also investigate the underlying mechanisms that attenuate spatial and temporal noises in both extra and intra-cellular spaces to enable formation of distinct regions with sharp boundaries consisting different cell types. In particular, we will investigate two biology systems: regeneration of colonic crypt and development of zebrafish hindbrain, using stochastic PDE models and simulations with moving boundaries.

Models of Cell Polarization and Motility

Speaker: 

Leah Keshet

Institution: 

University of British Columbia

Time: 

Monday, December 10, 2012 - 4:00pm

Location: 

RH306

Abstract:  In order to fight infection or heal injury, living cells have to be able to move in response to chemical cues around them. As a first step, an internal chemical "map" is rapidly induced in the cell, leading to its polarization, reorganization of structural proteins (cytoskeleton), shape change, and crawling motility. In my talk, I will summarize some of the work done in my group addressing these processes. I will explain the basic properties of the signalling proteins (small GTPases) and their role in cell polarization. I will motivate a sequence of mathematical models that we have studied to understand the underlying mechanisms. One theme in my talk will be the cross-fertilization of the complex biological problem and its simplified mathematical caricatures. Another theme is the effect of cell shape on internal chemical dynamics. I will conclude with recent developments on computations of cell shape dynamics in 2D simulations.

Professor Qing Nie Receives an NSF Award of $2M

Mathematics and biomedical engineering professor Qing Nie and biological chemistry professor Xing Dai have been awarded $2 million by the National Science Foundation to study epithelial tissue development and regulation using mathematical models and systems biology experimental methods. "This award reflects the strong interdisciplinary collaboration promoted by the Center for Mathematical & Computational Biology," said center director Nie.

Minimal tori in S^3 and the Lawson Conjecture

Speaker: 

Simon Brendle

Institution: 

Stanford University

Time: 

Tuesday, October 2, 2012 - 4:00pm

Location: 

RH 306

In 1966, Almgren showed that any immersed minimal surface in
S^3 of genus 0 is totally geodesic, hence congruent to the equator. In
1970, Blaine Lawson constructed many examples of minimal surfaces in S^3
of higher genus; he also constructed numerous examples of immersed minimal
tori. Motivated by these results, Lawson conjectured that any embedded
minimal surface in S^3 of genus 1 must be congruent to the Clifford
torus.

In this talk, I will describe a proof of Lawson's conjecture. The proof
involves an application of the maximum principle to a function that depends
on a pair of points on the surface.

Math Club Kick-off Meeting

All are welcome to the 2012-2013 Anteater Mathematics Club organizational meeting!
Come and meet fellow math enthusiasts. At this kick-off meeting we will play some fun ice-breaker games, elect club officers for the year and plan upcoming club events.
Pizza and soda will be served!

Applying to Math Grad School Workshop

Come learn about Applying to Mathematics Graduate School!
We will discuss everything from preparing for grad school, choosing schools, the application process and what to expect once enrolled. This workshop is designed for sophomores, juniors and seniors who are thinking about attending graduate school in mathematics. Students who are graduating this year and applying to graduate school are strongly encouraged to attend.

Automated measurements from digital media enable better modeling: Vascular geometry, consumer-resource interactions, and bacterial colony sizes

Speaker: 

Van Savage

Institution: 

UCLA

Time: 

Monday, December 3, 2012 - 12:00pm to 1:00pm

Host: 

Location: 

3201 Natural Sciences 2

Tools now exist that enable the extraction of data from images and video for a wide-range of biological systems. I use these approaches to implement high-throughput methods that often yield higher-quality data, new types of data, and substantially more data than previous efforts. I will discuss three examples connected to ongoing research in my lab. First, I will describe new software for automatically measuring vessel dimensions and geometry from three-dimensional angiographic (e.g., CT and MRI) images. Because these measurements are non-invasive, we can avoid concerns about distortion or destruction of the vasculature, thus leading to more reliable measurements. Second, I will show how video-tracking software is being used to track wingless fruit flies that are being hunted by wolf spiders. These high-resolution measurements allow us to study components of consumer-resource interactions that have rarely been measured before. Finally, I will outline new software to identify individual bacterial colonies grown in agar plates, measure their sizes, and construct size distributions. With these measurements, we can analyze how the phenotype of colony size, including coefficient of variation and other measures of the size distribution, responds to a range of concentrations of antibiotics, potentially helping to reveal how bacterial diversity relates to the evolution of resistance.

Multi-physics domain decomposition methods for Stokes-Darcy model

Speaker: 

Xiaoming He

Institution: 

Missouri University of Science & Technology

Time: 

Monday, October 29, 2012 - 4:00pm to 5:00pm

Host: 

Location: 

RH306

The Stokes-Darcy model arises in many interesting real world applications, including groundwater flows in karst aquifers, interaction between surface and subsurface flows, industrial filtrations, oil reservoir in vuggy porous medium, and so on. This model describes the free flow of a liquid by the Stokes or Navier-Stokes equation and the confined flow in a porous media by the Darcy equation; the two flows are coupled through interface conditions. For the problems mentioned, the resulting coupled Stokes-Darcy model has higher fidelity than either the Darcy or Stokes systems on their own. However, coupling the two constituent models leads to a very complex system.

This presentation discusses multi-physics domain decomposition methods for solving the coupled Stokes-Darcy system. Robin boundary conditions based on the physical interface conditions are utilized to decouple the Stokes and Darcy parts of the system. A parallel iterative domain decomposition method is first constructed for the steady state Stokes-Darcy model with the Beavers-Joseph interface condition. Then two parallel non-iterative domain decomposition methods are proposed for the time-dependent Stokes-Darcy model with the Beavers-Joseph-Saffman interface condition. Numerical examples are presented to illustrate the features of these methods and verify the theoretical results.

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