Linear Mixed Effect Models and Gene-Gene Interaction: Something Old, Something New ...

Speaker: 

Janet Sinsheimer

Institution: 

UCLA

Time: 

Monday, November 13, 2017 - 4:00pm to 5:00pm

Host: 

Location: 

RH 306

Linear mixed effect models (LMMs) have a long history in genetics, going back at least as far as when R. A . Fisher proposed the polygenic model and have become a main stay in statistical modeling.  Because they can be computationally intense, LMMs were dropped in favor of simpler statistical tests in the whole genome era of genetics.  However, quite recently LMMs surged in popularity for -omic studies and in particular for genome wide association studies.  In my talk, I will review what makes these models so popular now in genomics, discuss my groups’ recent work with LMMs to detect maternal gene by offspring gene interactions, and then touch on some open questions. 

A generalization of the KdV hierarchy to canonical systems.

Speaker: 

Darren Ong

Institution: 

Xiamen University Malaysia

Time: 

Wednesday, September 6, 2017 - 2:00pm

Title:

 

 

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Abstract:

(Joint work with Injo Hur)

 The KdV equation has many connections in many different parts of mathematics and physics. For example, it is of critical importance in the inverse spectral theory of the Schrödinger operator, since it describes a way to evolve a Schrödinger operator that keeps its spectrum invariant. This evolution is known as the KdV hierarchy.

Another useful perspective on the inverse spectral theory of the Schrödinger operator is that of the Herglotz m-function. To each Schrödinger operator we associate a holomorphic function from the upper half-plane to itself, such that the limiting behavior of this function on the real line determines the spectrum of the Schrödinger operator. 

We combine these two perspectives on inverse spectral theory, and introduce a version of the KdV hierarchy that applies to all holomorphic functions from the upper half-plane to itself, not just the ones that are associated to a Schrödinger operator. This approach suggests a way to unify a large class of isospectral evolutions for many different operators.

The dispersive and Strichartz estimates for free Laplacian

Speaker: 

Wencai Liu

Institution: 

UC Irvine

Time: 

Tuesday, April 18, 2017 - 10:00am to 10:50am

Location: 

RH 510M

The goal of this Seminar is to give an introduction of the dispersive and Strichartz estimates. I will present a new way to the proof of dispersive estimate which is easy to be extended to manifold. Using $TT*$ arguments and dispersive estimate, I will set up the Strichartz estimate. In order to simplify the Seminar, I will focus on the free laplacian.

Mutual Stationarity

Speaker: 

Omer Ben Neria

Institution: 

UCLA

Time: 

Monday, May 1, 2017 - 4:00pm to 5:30pm

Host: 

Location: 

RH 440R

Mutual stationarity is a notion of infinite products of stationary sets introduced by Foreman and Magidor. The assertion that an infinite sequence of stationary sets is mutually stationary has a natural model theoretic interpretation and can be viewed as a strengthening of the Loewenheim-Skolem property.

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